Dr. Priori is a leading scientist in the field of long-QT syndrome. She is a clinical cardiologist specializing in the field of inherited arrhythmia syndromes.  Her research focuses on the genetic components of cardiac defects and their electrophysiological consequences.  Dr. Priori has authored and co-authored many peer-reviewed articles and has received several awards and honors including BCVS Thomas Smith Memorial Lecture of the American Heart Association; “ESC Silver Medal, Outstanding contribution development of Scientific Guidelines”; Conferimento della “The Michel Mirowski Lectureship” della John Hopkins University, Baltimore, USA.; Member of the Board of the SADS Foundation; “Scholar in Cardiology” – Italian Society of Cardiology; and Outstanding Research Award in Pediatric Cardiology of the American Heart Association.

Honors, Awards, and Organizations
Douglas Zipes Lectureship Award, Heart Rhythm Society, 2007
BCVS Thomas Smith Memorial Lecture, American Heart Association, 2006
European Society of Cardiology Silver Medal, 2006
Scholar in Cardiology, Italian Society of Cardiology, 2002
Member of the Board, European Society of Cardiology, 2002
Outstanding Research Award in Pediatric Cardiology, American Heart Association, 2001
Chairman, Task Force on Sudden Cardiac Death, European Society of Cardiology, 2000

Recent Publications

Dybkova N, Sedej S, Napolitano C, Neef S, Rokita AG, Hünlich M, Brown JH,
Kockskämper J, Priori SG, Pieske B, Maier LS. Overexpression of CaMKIIδc in
RyR2R4496C+/- knock-in mice leads to altered intracellular Ca2+ handling and
increased mortality. J Am Coll Cardiol. 2011 Jan 25;57(4):469-79. PubMed PMID:
21251589.

Liu N, Ruan Y, Denegri M, Bachetti T, Li Y, Colombi B, Napolitano C, Coetzee
WA, Priori SG. Calmodulin kinase II inhibition prevents arrhythmias in
RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia.
J Mol Cell Cardiol. 2011 Jan;50(1):214-22. Epub 2010 Oct 23. PubMed PMID:
20937285.

Huang H, Priori SG, Napolitano C, O'Leary ME, Chahine M. Y1767C, a novel SCN5A
mutation, induces a persistent Na+ current and potentiates ranolazine inhibition
of Nav1.5 channels. Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H288-99.
Epub 2010 Nov 12. PubMed PMID: 21076026.

Schwartz PJ, Spazzolini C, Priori SG, Crotti L, Vicentini A, Landolina M,
Gasparini M, Wilde AA, Knops RE, Denjoy I, Toivonen L, Mönnig G, Al-Fayyadh M,
Jordaens L, Borggrefe M, Holmgren C, Brugada P, De Roy L, Hohnloser SH, Brink PA.
Who are the long-QT syndrome patients who receive an implantable
cardioverter-defibrillator and what happens to them?: data from the European
Long-QT Syndrome Implantable Cardioverter-Defibrillator (LQTS ICD) Registry.
Circulation. 2010 Sep 28;122(13):1272-82. Epub 2010 Sep 13. PubMed PMID:
20837891.

Priori SG. The fifteen years of discoveries that shaped molecular
electrophysiology: time for appraisal. Circ Res. 2010 Aug 20;107(4):451-6.
Review. PubMed PMID: 20724724.

Kang G, Giovannone SF, Liu N, Liu FY, Zhang J, Priori SG, Fishman GI. Purkinje
cells from RyR2 mutant mice are highly arrhythmogenic but responsive to targeted
therapy. Circ Res. 2010 Aug 20;107(4):512-9. Epub 2010 Jul 1. PubMed PMID:
20595652; PubMed Central PMCID: PMC2930621.

Tomás M, Napolitano C, De Giuli L, Bloise R, Subirana I, Malovini A, Bellazzi
R, Arking DE, Marban E, Chakravarti A, Spooner PM, Priori SG. Polymorphisms in
the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long
QT syndrome. J Am Coll Cardiol. 2010 Jun 15;55(24):2745-52. PubMed PMID:
20538168.

Herron TJ, Milstein ML, Anumonwo J, Priori SG, Jalife J. Purkinje cell
calcium dysregulation is the cellular mechanism that underlies catecholaminergic
polymorphic ventricular tachycardia. Heart Rhythm. 2010 Aug;7(8):1122-8. Epub
2010 Jun 9. PubMed PMID: 20538074; PubMed Central PMCID: PMC2910215.