Department of Internal Medicine
Infectious Diseases Faculty
Daniel J. Diekema, M.D., M.S.
Clinical Associate Professor of Medicine and Pathology
Dr. Diekema's research focuses on hospital-acquired fungal infections, antimicrobial resistance, molecular epidemiology, and hospital epidemiology.
His current projects include:
- Retrospective study of the epidemiology of nosocomial Candida spp. bloodstream infection at the University of Iowa, including trends in species distribution, antifungal susceptibility, crude and attributable mortality, and patterns of antifungal use.
- Local principle investigator for a prospective study of the epidemiology of invasive fungal infections in hospitalized patients (the PATH Alliance study).
- Principle investigator for two international antifungal resistance surveillance studies.
- Coinvestigator for ongoing studies of the epidemiology of community-associated methicillin-resistant Staphylococcus aureus (MRSA) in the State of Iowa.
- Coinvestigator for a study of the efficacy of rapid (real-time PCR) detection of MRSA and vancomycin-resistant enterococci (VRE) in the prevention of resistant organism transmission in the Iowa City Veterans Affairs Medical Center (VA grant, PI: Patricia Winokur, MD).
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Medical School:
Vanderbilt University
Residency:
University of Virginia
Fellowships:
The University of Iowa
Infectious Diseases, 1992-95
Medical Microbiology, 1998-00 |
Honors, Awards, and Organizations
- Catherine Easterling Mountcastle Scholarship, Vanderbilt University School of Medicine, 1985-89
- Alpha Omega Alpha Medical Honor Society, 1987
- Upjohn Achievement Award for Academic Excellence, Vanderbilt University School of Medicine, 1989
- Founder's Medal (for graduating first in class), Vanderbilt University School of Medicine, 1989
- Fellow, American College of Physicians
- Fellow, Society for Healthcare Epidemiology of America
- Chair-Elect, Division L, American Society for Microbiology
Recent Publications
- Flanagan M, Ramanujam R, Sutherland J, Vaughn T, Diekema DJ, Doebbeling BN. Development and validation of measures to assess prevention and control of antimicrobial resistance in hospitals. Medical Care 2007;45:537-44.
- Diekema DJ, Edmond MB. Look before you leap: Active surveillance for multidrug resistant organisms. Clin Infect Dis 2007;44:1101-1107.
- Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: A persistent public health problem. Clin Microbiol Rev 2007;20:133-163.
- Polgreen PM, Chen YY, Cavanaugh JE, Ward M, Coffman S, Hornick DB, Diekema DJ, Herwaldt LA. An outbreak of severe Clostridium difficile-associated disease possibly related to inappropriate antimicrobial therapy for community-acquired pneumonia. Infect Control Hosp Epidemiol 2007;28:212-214.
- Zhao X, Oh S, Jajko R, Diekema DJ, Pfaller MA, Pujol C, Soll DR, Hoyer LL. Analysis of ALS5 and ALS6 allelic variability in a geographically diverse collection of Candida albicans isolates. Fungal Genetics and Biology; ePub ahead of print, June 2, 2007.
- Andrews JI, Fleener DK, Messer SA, Hansen WF, Pfaller MA, Diekema DJ. The Yeast Connection – is Candida linked to breastfeeding associated pain? Am J Obstet Gynecol 2007;197:427-429.
- Pfaller MA, Diekema DJ, Procop G, Rinaldi M. Multicenter comparison of the VITEK 2 Yeast Susceptibility Test with the CLSI broth microdilution reference method for testing amphotericin B, flucytosine and voriconazole against Candida spp. J Clin Microbiol 2007;ePub ahead of print, October 3, 2007.
- Klevay M, Ernst E, Miller J, Hollanbaugh J, Pfaller M, Diekema DJ. Therapy and Outcome of Candida glabrata versus Candida albicans bloodstream infection. Diagn Microbiol Infect Dis 2007 (in press).
- Lockhart SR, Messer SA, Pfaller MA, Diekema DJ. Lodderomyces elongisporus masquerading as Candida parapsilosis as a cause of bloodstream infections. J Clin Microbiol 2007 (in press).
- Huang SS, Diekema DJ, Warren DK, Zuccotti G, Winokur PL, Tendolkar S, Boyken L, Datta R, Jones RM, Ward M, Aubrey T, Onderdonk A, Platt R. Strain relatedness of isolates from patients with serial methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis 2008 (in press).
- Pfaller MA, Boyken L, Hollis RJ, Kroeger J, Messer SA, Tendolkar S, Diekema DJ. In vitro susceptibility of Candida spp. to anidulafungin, caspofungin, and micafungin: Six years of global surveillance. J Clin Microbiol 2008 (in press).
- Andes D, Diekema DJ, Pfaller MA, Prince RA, Marchillo K, Ashbeck J, and Hou J. In vivo pharmacodynamic characterization of anidulafungin in a neutropenic murine candidiasis model. Antimicrob Agents Chemother 2008 (in press)
- Click here for additional publications.
Links of Interest
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