The University of Iowa Carver College of Medicine

Electron Spin Resonance Facility

Free Radicals in Biology

The following papers were generated by students from Graduate Course Free Radicals in Biology and Medicine (77:222) 2001.

Instructors

  • Garry R. Buettner, Ph.D.
  • Larry W. Oberley, Ph.D.

Please Note

In view of the possibility of human error or changes in our knowledge due to continued research, neither the authors nor The University of Iowa nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they are not responsible for any errors or omissions or for the results obtained from the use of such information. Readers are encouraged to confirmthe information contained herein with other sources.

All material contained in these papers is copyright of the papers' author, or the owner of the source that the material was taken from. These works are not intended as threats to the ownership of said copyrights.

Paper 1

  Author Title  pdf 
Abdalla, Maher Y. Peroxynitrite pdf available
Ahmad, Iman Hydrogen Peroxide (H2O2) pdf available
Andringa, Kelly K. Methyl Radical: Just Like Mother's Little Helper pdf available
Banulescu, Sultana Nitric Oxide: The Magic Gas of John Dalton and John Priestley pdf available
Hu, Jianfang Hydroxyl Radical pdf available
Kirsch, Jeffrey D. The Chemistry of Sulfenic Acids pdf available
Li, Ling Glutathiyl Radicals: A Mini Review pdf available
Luo, Jun Singlet Oxygen pdf available
Ott, Michael L. The Peroxyl Radical pdf available
Peters, Sabina S. Superoxide (O2·-): An Introductory Glimpse From the Chemical/Biochemical Perspective pdf available
Pfaffly, Jennifer R. Glucose: A Little Goes a Long Way pdf available
Rose, Patricia A. Superoxide pdf available
Rovinsky, Sherry A. Hydrogen Peroxide: An Ubiquitous Reactive Oxygen Species pdf available
Sun, Wenqing Glutathiyl Radical pdf available
Wang, Min Peroxyl Radical and Lipid Peroxidation pdf available
Zhao, Lingjie Singlet Oxygen pdf available

Paper 2

  Author Title  pdf 
Abdalla, Maher Y. Vitamin Excellent pdf available
Ahmad, Iman Pyruvate pdf available
Andringa, Kelly K. b-Carotene: The Reason Not to Feed Your Veggies to the Dog pdf available
Banulescu, Sultana Zinc: From Marco Polo to Transcriptional Control pdf available
Hu, Jianfang Is b-Carotene an Antioxidant? pdf available
Kirsch, Jeffrey D. Flavonoids: The Good, the Bad and the Ugly pdf available
Li, Ling Nitric Oxide as an Antioxidant pdf available
Luo, Jun Nitroxides - Metal-Independent SOD Mimics pdf available
Ott, Michael L. Desferrioxamine pdf available
Peters, Sabina S. Ebselen as a Glutathione Peroxidase Mimic: Alias Chemical Chameleon Antioxidant pdf available
Pfaffly, Jennifer R. Lipoic Acid: The Antioxidant Chameleon pdf available
Rose, Patricia A. Bilirubin: More Than Just Coloring for Bruises pdf available
Rovinsky, Sherry A. NAC: It's Not Just for Glutathione Anymore pdf available
Sun, Wenqing Metal-Dependent SOD Mimics pdf available
Wang, Min SOD Mimics pdf available
Zhao, Lingjie Glutathione, a Ubiquitous Thiol pdf available

Paper 3

  Author Title  pdf 
Abdalla, Maher Y. NADPH Oxidase, The Macrophage Killing Weapon pdf available
Ahmad, Iman Catalase pdf available
Andringa, Kelly K. Heat Shock Protein 90: A Family Affair pdf available
Banulescu, Sultana Melanin: What Michael Jackson Didn't Know pdf available
Hu, Jianfang Molecular Chaperones: Heat Shock Protein 70 pdf available
Kirsch, Jeffrey D. The Chemistry of Peroxiredoxins pdf available
Li, Ling Xanthine Oxidase pdf available
Luo, Jun Manganese Superoxide Dismutase (MnSOD) pdf available
Ott, Michael L. Lactoperoxidase pdf available
Peters, Sabina S. Copper Zinc Superoxide Dismutase pdf available
Pfaffly, Jennifer R. Glucose Transporters: A GLUTton for Vitamin C pdf available
Rose, Patricia A. Thioredoxin: A Tale of Two Cysteines pdf available
Rovinsky, Sherry A. Thioredoxin: An Unauthorized Biography pdf available
Sun, Wenqing Manganese Superoxide Dismutase pdf available
Wang, Min Hypoxia Inducible Factor-1: The Guardian Working in Hypoxia pdf available
Zhao, Lingjie Phospholipid Hydroperoxide Glutathione Peroxidase (PhGPx) - An Often Overlooked Antioxidant Enyzme pdf available

Paper 4

  Author Title  pdf 
Abdalla, Maher Y. Cigarette Smoking and DNA Damage pdf available
Ahmad, Iman Buthionine Sulfoximine: Glutathione Depleter pdf available
Andringa, Kelly K. Adriamycin: As Good As it Gets pdf available
Banulescu, Sultana Chlorpromazine: For Better For Worse
pdf available
Hu, Jianfang Nitroglycerine pdf available
Kirsch, Jeffrey D. Acetaminophen: A Wolf in Sheep's Clothing pdf available
Li, Ling Streptozotocin
pdf available
Luo, Jun Ultraviolet Radiation and Skin Carcinogenesis pdf available
Ott, Michael L. Photodynamic Therapy: You down with PDT? Yeah You Know Me! pdf available
Peters, Sabina S. Asbestos: A Particular Matter pdf available
Pfaffly, Jennifer R. Gliclazide pdf available
Rose, Patricia A Gloves to Balloons: Incidence of Latex Allergy is on the Rise pdf available
Rovinsky, Sherry A. Diamide for Dummies pdf available
Sun, Wenqing 1,3-bis-Chloroethyl-1-Nitrosourea (BCNU) pdf available
Wang, Min Nicotine: The Masked Killer pdf available
Zhao, Lingjie Bleomycin: An Antitumor Antibiotic pdf available

Paper 5

  Author Title  pdf 
Abdalla, Maher Y.

Alcohol and Liver Diseases

pdf available
Ahmad, Iman Glucose Metabolism and Cancer Therapy pdf available
Andringa, Kelly K. Amyotrophic Lateral Sclerosis: A Scientific Odyssey pdf available
Banulescu, Sultana Shaking Palsy: The Role of Free Radicals in the Pathophysiology of Parkinson's Disease pdf available
Hu, Jianfang Oxidative Stress and Aging pdf available
Li, Ling Oxidative Stress in Alzheimer's Disease pdf available
Luo, Jun The Role of Antioxidants in Myocardial Ischemia-Reperfusion Injury pdf available
Ott, Michael L. Malaria: Not Just a Case of Bad Air pdf available
Peters, Sabina S. Parkinson's : Keep Plugging the Meter pdf available
Pfaffly, Jennifer R. Diabetic Complications, Hyperglycemia & Free Radicals pdf available
Rose, Patricia A. Influenza Infection: Nothing to Sneeze At pdf available
Rovinsky, Sherry A. Aging and Free Radicals: Is Dietary Restriction Really a Fountain of Youth? pdf available
Sun, Wenqing Reactive Oxygen Species and Breast Cancer Carcinogenesis pdf available
Wang, Min Atherosclerosis: The Past, the Present and the Future pdf available
Zhao, Lingjie Effects of Free Radicals in Diabetes pdf available

Appendix

  Author Title  pdf 
Buettner, Garry R. The Pecking Order of Free Radicals and Antioxidants: Lipid Peroxidation, a-Tocopherol, and Ascorbate Arch Biochem Biophys 1993, 300: 535-543 pdf available
Schafer, Freya Q. et al. Redox Environment of the Cell as Viewed through the Redox State of the Glutathione Disulfide/Glutathione Couple Free Radic Biol Med 2001, 30: 1191-1212 pdf available
Hempel, Stephen L. et al. Dihydrofluorescein Diacetate Is Superior for Detecting Intracellular Oxidants: Comparison with 2',7'- Dichlorodihydrofluorescein Diacetate, 5(and 6)-Carboxy-2',7'-Dichlorodihydrofluorescein Diacetate, and Dihydrorhodamine 123 Free Radic Biol Med 1999, 27: 146-159 pdf available
Qian, Steven Yue et al. Iron and Dioxygen Chemistry Is an Important Route to Initiation of Biological Free Radical Oxidations: An Electron Paramagnetic Resonance Spin Trapping Study Free Radic Biol Med 1999, 26: 1447-1456 pdf available
Venkataraman, Sujatha et al. Detailed Methods for the Quantification of Nitric Oxide in Aqueous Solutions Using Either an Oxygen Monitor or EPR Free Radic Biol Med 2000, 29: 580-585 pdf available
Kelley, Eric E. et al. Relative a-Tocopherol Deficiency in Cultured Cells: Free Radical-Mediated Lipid Peroxidation, Lipid Oxidizability, and Cellular Polyunsaturated Fatty Acid Content Arch Biochem Biophys 1995, 319: 102-109 pdf available
Wagner, Brett A. et al. Vitamin E Slows the Rate of Free Radical-Mediated Lipid Peroxidation in Cells Arch Biochem Biophys 1996, 334: 261-267 pdf available