The University of Iowa Carver College of Medicine

Protein Crystallography Facility

Services

  • Protein purity analysis by dynamic light scattering
  • Set-up of crystallization screens using commercial and facility-made conditions
  • Preliminary screening of crystals
  • Data collection of quality crystals at facility x-ray source and synchrotrons
  • Data processing using popular packages such as d*TREK and XDS
  • Structure determination using MR, MIR, MAD, SAD, techniques and software such as ccp4, CNS, SHELX, and PHENIX
  • Structure refinement and fitting using Refmac, Coot, O
  • Structure visualization and analysis using PyMol, Sybyl