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Alumni Interviews:
Yuan Chuan Lee, Ph.D.Yuan Chuan Lee, Ph.D.

’62 Ph.D. - Biochemistry
Recipient of 2004 Distinguished Alumni Award for Achievement

"I receive the greatest satisfaction from seeing the success of former students and their appreciation of my efforts."



Yuan Chuan Lee was drawn to glycoscience as a graduate student working with Rex Montgomery, PhD, UI professor of biochemistry, whose lessons encompassed more than simply science. When Lee offered to assist a fellow student, saying his own work was done for the day, Montgomery declared, "There is no such day for a scientist." Lee took the words to heart.

He since has become in internationally known investigator. Leaving Iowa, he did postdoctoral work at the University of California, Berkely, then joined the Johns Hopkins University faculty. He later returned to his native Taiwan as an Academia Sinica visiting professor, and also has held visiting appointments in Kyoto, Japan, and Beijing and Shanghai, China.

Lee’s work in analytical glycobiology, structural glycobiology and carbohydrate recognition has helped build glycoscience from a small division of biochemistry to an established field. Today it’s an important areas of postgenomic biology.

The synthetic proteins Lee’s lab created in the late 1970s boosted the speed and accuracy of experiments that showed how carbohydrates on cell surfaces affect cellular function and interactions. These and other findings have contributed to treatments for tissue rejection, hepatitis, nerve damage, cancer and inflammation.

Achievements like these have won Lee the prestigious Claud S. Hudson Award from the American Chemical Society, the C.H. Li Memorial Award from Academia Sinica and the National Institutes of Health Fogarty Fellowship. He has published more than 300 papers and has served as an executive editor for Analytical Biochemistry since 1978.

Outside the lab, Lee has written articles for Chinese and Japanese publications, including one chosen among the top 60 essays published in Japan. He also is an avid chamber musician.

He passes on the lessons he’s learned through his commitment to students. At this point in his career, he said, he receives the greatest satisfaction from "seeing the success of former students and their appreciation of my efforts."

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